Seven adjustments for Crystal Palace from the aspect that started the 4-3 defeat at Liverpool on 19 January.
Ahead Connor Wickham makes a rare originate whereas keeper Julian Speroni, defender Patrick van Aanholt, midfielder Cheikhou Kouyate and ahead Wilfried Zaha are the survivors from Anfield.
Crystal Palace XI: Speroni, Ward, Kelly, Dann, Van Aanholt, Meyer, Kouyate, Schlupp, Townsend, Zaha, Wickham.
Substitutes: Tupper, Wan-Bissaka, Sakho, Riedewald, Milivojevic, Benteke, Ayew.
Tottenham also make seven adjustments from the aspect that crashed out of the Carabao Cup on Thursday.
French winger Georges-Kevin N’Koudou makes his first Spurs originate since December 2017. Paulo Gazzaniga, Jan Vertonghen, Eric Dier and Fernando Llorente, who all started the closing sport, play at Selhurst Park.
Tottenham XI: Gazzaniga, Trippier, Sanchez, Foyth, Vertonghen, Walker-Peters, Dier, Skipp, Nkoudou, Lucas, Llorente.
Substitutes: Lloris, Aurier, Rose, Wanyama, Winks, Lamela, Sterling.